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dCeMM2

dCeMM2
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Purity:99.68%
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dCeMM2

Catalog No. T61477Cas No. 296771-07-8
dCeMM2 is a glue degrader. dCeMM2 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, leading to the ubiquitination and degradation of cyclin K.
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Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$72In Stock
10 mg$122In Stock
25 mg$263In Stock
50 mg$449In Stock
100 mg$667In Stock
500 mg$1,420In Stock
1 mL x 10 mM (in DMSO)$112In Stock
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Product Introduction

Bioactivity
Description
dCeMM2 is a glue degrader. dCeMM2 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, leading to the ubiquitination and degradation of cyclin K.
Chemical Properties
Molecular Weight370.82
FormulaC16H11ClN6OS
Cas No.296771-07-8
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 16.7 mg/mL (45.0 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6967 mL13.4836 mL26.9673 mL134.8363 mL
5 mM0.5393 mL2.6967 mL5.3935 mL26.9673 mL
10 mM0.2697 mL1.3484 mL2.6967 mL13.4836 mL
20 mM0.1348 mL0.6742 mL1.3484 mL6.7418 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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