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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $38 | In Stock | |
2 mg | $54 | In Stock | |
5 mg | $89 | In Stock | |
10 mg | $155 | In Stock | |
25 mg | $355 | In Stock | |
50 mg | $597 | In Stock | |
100 mg | $852 | In Stock | |
500 mg | $1,730 | In Stock | |
1 mL x 10 mM (in DMSO) | $97 | In Stock |
Description | HQ461 is a molecular gel that promotes CDK12-DDB1 interactions and triggers cyclin K degradation, which impairs CDK12 function, leading to decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death. |
Molecular Weight | 345.44 |
Formula | C15H15N5OS2 |
Cas No. | 1226443-41-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 62 mg/mL (179.48 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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