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Desmethyl Celecoxib

Desmethyl Celecoxib
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Purity:99.98%
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Desmethyl Celecoxib

Catalog No. T11005Cas No. 170569-87-6
Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM). with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%.
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Pack SizePriceAvailabilityQuantity
10 mg$41In Stock
25 mg$74In Stock
50 mg$126In Stock
100 mg$207In Stock
200 mg$310In Stock
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Related Compound Libraries of "Desmethyl Celecoxib"

Product Introduction

Bioactivity
Description
Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM). with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%.
Chemical Properties
Molecular Weight367.35
FormulaC16H12F3N3O2S
Cas No.170569-87-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 70 mg/mL (191 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7222 mL13.6110 mL27.2220 mL136.1100 mL
5 mM0.5444 mL2.7222 mL5.4444 mL27.2220 mL
10 mM0.2722 mL1.3611 mL2.7222 mL13.6110 mL
20 mM0.1361 mL0.6805 mL1.3611 mL6.8055 mL
50 mM0.0544 mL0.2722 mL0.5444 mL2.7222 mL
100 mM0.0272 mL0.1361 mL0.2722 mL1.3611 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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