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DETA NONOate
🥰Excellent
Catalog No. T36033Cas No. 146724-94-9
Alias NOC-18, Diethylamine NONOate
DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infected wounds.
DETA NONOate
🥰Excellent
Purity: 98.00%
Catalog No. T36033Alias NOC-18, Diethylamine NONOateCas No. 146724-94-9
DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infected wounds.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock |
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CitedSelect Batch
Purity:98.00%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infected wounds. |
| In vitro | By reducing the expression of glycopeptidolipids (GPL) in M. abscessus subspecies abscessus (Mab), DETA NONOate (100 μM; 16 h) induces the growth of nontuberculous mycobacteria (NTM) complex in the R morphotype[3]. |
| In vivo | DETA NONOate (15-150 μg/rat, intracerebroventricular injection, once) activates nociceptors in the formalin model in rats[4] and, at 1 µM, reduces ischemia or ischemia/reperfusion-induced mitochondrial damage in the heart while preventing apoptotic cell death[2]. |
| Alias | NOC-18, Diethylamine NONOate |
| Molecular Weight | 163.18 |
| Formula | C4H13N5O2 |
| Cas No. | 146724-94-9 |
| Smiles | CCNCC.CCN(CC)N(O)N=O |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | aqueous buffers: >100 mg/mL H2O: 30 mg/mL (183.85 mM), when pH is adjusted to 9 with NaOH. Sonication is recommended. DMSO: <1 mg/mL (Insoluble) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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