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DPTN dihydrochloride
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DPTN dihydrochloride
Catalog No. T72067Cas No. 325767-87-1
DPTN dihydrochloride is a potent and selective A3AR antagonist with Ki values of 1.65, 9.61 and 8.53 nM in human, mouse and rat, respectively.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $43 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $168 | In Stock | |
| 25 mg | $365 | In Stock | |
| 50 mg | $562 | In Stock | |
| 100 mg | $790 | In Stock | |
| 500 mg | $1,670 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | DPTN dihydrochloride is a potent and selective A3AR antagonist with Ki values of 1.65, 9.61 and 8.53 nM in human, mouse and rat, respectively. |
| In vitro | DPTN dihydrochloride is a potent antagonist of human, mouse, and rat A3AR. However, compared with human A3AR, DPTN dihydrochloride has a weaker effect and reduced selectivity in mice and rats (approximately 20 times that of A2BAR).[1] The binding affinity test of DNPT (10 μM) on the cell membrane of transfected HEK293 cells showed that its Ki values for hA1, hA2A, hA2B and hA3 were 162±49, 121±42, 230±40 and 1.65±0.57 nM respectively[ 1]. The Ki values of DPTN dihydrochloride at A1, A2A, A2B and A3 receptors are 411, 830, 189 and 9.61 nM (mouse); 333, 1147, 163 and 8.53 nM (rat) respectively.[1] |
| Molecular Weight | 459.39 |
| Formula | C22H20Cl2N4OS |
| Cas No. | 325767-87-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||
| Solubility Information | DMSO: 2.30 mg/mL (5 mM) | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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