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Eeyarestatin I

Catalog No. T27240Cas No. 412960-54-4

Eeyarestatin I is an inhibitor that inhibits the degradation and translocation of ER-associated proteins. Eeyarestatin I is associated with the p97 deubiquitination process and inhibits atx3 deubiquitination. Eeyarestatin I has anticancer effects by inducing proteins that cause cell death.

Eeyarestatin I

Eeyarestatin I

Purity: 98%
Catalog No. T27240Cas No. 412960-54-4
Eeyarestatin I is an inhibitor that inhibits the degradation and translocation of ER-associated proteins. Eeyarestatin I is associated with the p97 deubiquitination process and inhibits atx3 deubiquitination. Eeyarestatin I has anticancer effects by inducing proteins that cause cell death.
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2 mgInquiry5 days
25 mgInquiry8-10 weeks
50 mgInquiry5 days
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Purity:98%
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Product Introduction

Bioactivity
Description
Eeyarestatin I is an inhibitor that inhibits the degradation and translocation of ER-associated proteins. Eeyarestatin I is associated with the p97 deubiquitination process and inhibits atx3 deubiquitination. Eeyarestatin I has anticancer effects by inducing proteins that cause cell death.
Targets&IC50
p97:> 30 μM, UbG76V-GFP:3.7 μM
Chemical Properties
Molecular Weight630.44
FormulaC27H25Cl2N7O7
Cas No.412960-54-4
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (35.7 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5862 mL7.9310 mL15.8619 mL79.3097 mL
5 mM0.3172 mL1.5862 mL3.1724 mL15.8619 mL
10 mM0.1586 mL0.7931 mL1.5862 mL7.9310 mL
20 mM0.0793 mL0.3965 mL0.7931 mL3.9655 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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