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Enavatuzumab
🥰Excellent
Catalog No. T76865Cas No. 1062149-33-0
Alias PDL-192, PDL192, Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody, ABT-361, ABT361
Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting the TWEAK receptor (TWEAKR), with anti-tumor activity. It induces tumor growth inhibition by recruiting and activating myeloid effectors to kill tumor cells. It is used in late-stage solid tumor research.
Enavatuzumab
Enavatuzumab
🥰Excellent
Catalog No. T76865Alias PDL-192, PDL192, Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody, ABT-361, ABT361Cas No. 1062149-33-0
Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting the TWEAK receptor (TWEAKR), with anti-tumor activity. It induces tumor growth inhibition by recruiting and activating myeloid effectors to kill tumor cells. It is used in late-stage solid tumor research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $228 | In Stock | |
| 5 mg | $622 | In Stock | |
| 10 mg | $993 | In Stock | |
| 25 mg | $1,470 | In Stock | |
| 50 mg | $1,980 | In Stock |
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CitedSelect Batch
Concentration:4.52 mg/mL
Purity:>95%
Contact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting the TWEAK receptor (TWEAKR), with anti-tumor activity. It induces tumor growth inhibition by recruiting and activating myeloid effectors to kill tumor cells. It is used in late-stage solid tumor research. |
| In vitro | Enavatuzumab has growth inhibiting activity in a wide range of cancer cell lines in vitro. Enavatuzumab (10 μg/mL) and cells incubated together for 24 hours resulted in significantly increased migration of immune effector cells to SN12C and A375 tumor cells. [1] |
| In vivo | Enavatuzumab achieved 70% tumor growth inhibition (TGI) in vivo against H358 tumors.[2] |
| Alias | PDL-192, PDL192, Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody, ABT-361, ABT361 |
| Cas No. | 1062149-33-0 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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