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FDI-6

🥰Excellent
Catalog No. T4005Cas No. 313380-27-7
Alias FDI6, FDI 6

FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.

FDI-6

FDI-6

🥰Excellent
Purity: 100%
Catalog No. T4005Alias FDI6, FDI 6Cas No. 313380-27-7
FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
Pack SizePriceAvailabilityQuantity
1 mg31 €In Stock
2 mg44 €In Stock
5 mg72 €In Stock
10 mg135 €In Stock
25 mg226 €In Stock
50 mg304 €In Stock
100 mg453 €In Stock
1 mL x 10 mM (in DMSO)79 €In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6(FDI6) binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
In vitro
FDI-6 specifically downregulates FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR. This small molecule-mediated effect is selective for FOXM1-controlled genes with no effect on genes regulated by homologous forkhead family factors.
AliasFDI6, FDI 6
Chemical Properties
Molecular Weight437.43
FormulaC19H11F4N3OS2
Cas No.313380-27-7
SmilesNc1c(sc2nc(cc(c12)C(F)(F)F)-c1cccs1)C(=O)Nc1ccc(F)cc1
Relative Density.1.562 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (114.3 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2861 mL11.4304 mL22.8608 mL114.3040 mL
5 mM0.4572 mL2.2861 mL4.5722 mL22.8608 mL
10 mM0.2286 mL1.1430 mL2.2861 mL11.4304 mL
20 mM0.1143 mL0.5715 mL1.1430 mL5.7152 mL
50 mM0.0457 mL0.2286 mL0.4572 mL2.2861 mL
100 mM0.0229 mL0.1143 mL0.2286 mL1.1430 mL

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