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FGH31
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Catalog No. T79312
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].
FGH31
FGH31
😃Good
Catalog No. T79312
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1]. |
| Targets&IC50 | D4 receptor:1.6 nM (Ki) |
| In vitro | Compound FGH31 (50 μM) exhibits a rate of decline in rat liver microsomes comparable to that of Imipramine [1]. Additionally, there is no evidence of P-glycoprotein (P-gp) mediated transport of FGH31 (50 μM, 4 h) in Caco-2 cells [1]. |
| Molecular Weight | 520.66 |
| Formula | C33H36N4O2 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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