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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $50 | In Stock | |
5 mg | $86 | In Stock | |
10 mg | $148 | In Stock | |
25 mg | $329 | In Stock | |
50 mg | $581 | In Stock | |
100 mg | $829 | In Stock | |
1 mL x 10 mM (in DMSO) | $94 | In Stock |
Description | FTBMT is a selective GPR52 agonist (EC50: 75 nM) and has antipsychotic and procognitive properties. |
Targets&IC50 | GPR52:75 nM(EC50) |
In vitro | In CHO cells expressing human, mouse, or rat GPR52, FTBMT (0.1-10 μM) improves intracellular cAMP levels (pEC50s of 7.03, 6.85, and 6.87, respectively)[2]. |
In vivo | In rats, FTBMT (3 or 10 mg/kg, 48 hours) improves recognition and spatial working memory. FTBMT (30 mg/kg, 90 minutes) shows antipsychotic-like activity without causing catalepsy in mice[2] |
Molecular Weight | 392.35 |
Formula | C19H16F4N4O |
Cas No. | 1358575-02-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (114.69 mM), Sonication is recommended. H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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