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Gentamicin
🥰Excellent
Catalog No. T25447Cas No. 1403-66-3
Alias Septigen, Refobacin, Oksitselanim, Lyramycin, Centicin
Gentamicin (Centicin) is a broad-spectrum aminoglycoside antibiotic with antibacterial activity, inhibiting the growth of Gram-positive and Gram-negative bacteria, and can be used to study ocular infections.
Gentamicin
🥰Excellent
Catalog No. T25447Alias Septigen, Refobacin, Oksitselanim, Lyramycin, CenticinCas No. 1403-66-3
Gentamicin (Centicin) is a broad-spectrum aminoglycoside antibiotic with antibacterial activity, inhibiting the growth of Gram-positive and Gram-negative bacteria, and can be used to study ocular infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $33 | In Stock | |
| 5 mg | $50 | In Stock | |
| 10 mg | $70 | In Stock | |
| 25 mg | $113 | In Stock | |
| 50 mg | $163 | In Stock | |
| 100 mg | $239 | In Stock | |
| 200 mg | $356 | In Stock |
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CitedSelect Batch
Potency:≥900IU/mg
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Product Introduction
Bioactivity
Chemical Properties
| Description | Gentamicin (Centicin) is a broad-spectrum aminoglycoside antibiotic with antibacterial activity, inhibiting the growth of Gram-positive and Gram-negative bacteria, and can be used to study ocular infections. |
| In vitro | Gentamicin was dissolved in EMEM and used in a final concentration of 200 μg/ml. All bacterial strains grew in the absence of antibiotics and all were grossly inhibited by Gentamicin. Gentamicin is superior to penicillin and streptomycin for control of bacterial growth in tissue culture. Its superiority in controlling P. aeruginosa, Proteus sp., and S. faecalis organisms. To this list may now be added Bacillus cereus, Klebsiella pneumoniae, Aeromonas, Enterobacter, Serratia, Citrobacter, and Alcaligenes faecalis. [1] |
| In vivo | In vivo efficacy of oxiconazole and Gentamicin combination in a murine superficial skin infection model. The combination of oxiconazole (2%) and Gentamicin (0.1%) reduced the bacterial load in skin by ~2.77 log10 CFU/gm and Gentamicin (~2.06 log10 CFU/gm) alone. These results indicate that the combination of Oxiconazole with gentamicin is potently active in vivo against S. aureus skin infections. [2] |
| Alias | Septigen, Refobacin, Oksitselanim, Lyramycin, Centicin |
| Molecular Weight | 477.60(Avervage) |
| Formula | C21H43N5O7 |
| Cas No. | 1403-66-3 |
| Smiles | CN[C@@H]1[C@H]([C@H](OC[C@@]1(O)C)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@H]3O[C@@H](CC[C@H]3N)CN)N)N)O.CN[C@@H]4[C@H]([C@H](OC[C@@]4(O)C)O[C@H]5[C@@H](C[C@@H]([C@H]([C@@H]5O)O[C@H]6O[C@H]([C@H](N)C)CC[C@H]6N)N)N)O.CN[C@@H]([C@@H]7CC[C@H]([C@H](O7)O[C@@H]8[C@H](C[C@H]([C@@H]([C@H]8O)O[C@H]9OC[C@](O)([C@@H]([C@H]9O)NC)C)N)N)N)C |
| Relative Density. | 1.3 g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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