gentamicin

Gentamicin is widely used as an antibiotic in the intensive care unit (ICU).

Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.

Gentamicin C1a, acting as the major component of the Gentamicin complex [1] [2], serves as the precursor to the semi-synthetic antibiotic Etimicin and exhibits antibacterial activity.

Micronomicin (Gentamicin C2b) is an antibiotic exhibiting antibacterial and bactericidal capacity.

Sisomicin Sulfate (Pathomycin) is the sulfate salt form of sisomicin, a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is structurally similar to gentamicin but has a unique unsaturated diamino sugar. Of the aminoglycoside antibiotics, sisomicin has the greatest activity against gram-positive bacteria.

Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM.

LCI peptide exhibits antimicrobial and antibacterial properties, effectively targeting plant pathogens such as Xanthomonas and Pseudomonas, as well as combating E. coli, Gentamicin-resistant MRSA, and Xoo [1].

Dalargin, a potent δ-opioid receptor agonist, demonstrates efficacy in mitigating cell death induced by Gentamicin and exhibits nephroprotective effects against Gentamicin-induced kidney injury. Additionally, Dalargin possesses antiulcer activity [1] [2] [3].

G-418 (Geneticin), an aminoglycoside antibiotic resembling gentamicin in structure, demonstrates toxicity to both eukaryotic and prokaryotic cells by obstructing protein synthesis [1].