Shopping Cart
- Remove All
Your shopping cart is currently empty
Glucocorticoid receptor agonist-1
🥰Excellent
Catalog No. T37908Cas No. 2166375-82-0
Glucocorticoid receptor agonist-1, a potent glucocorticoid receptor agonist, has an IC50 of 2.8 nM[1].
Glucocorticoid receptor agonist-1
🥰Excellent
Purity: 99.51%
Catalog No. T37908Cas No. 2166375-82-0
Glucocorticoid receptor agonist-1, a potent glucocorticoid receptor agonist, has an IC50 of 2.8 nM[1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $226 | In Stock | |
| 5 mg | $565 | In Stock | |
| 10 mg | $793 | In Stock | |
| 25 mg | $1,230 | In Stock | |
| 50 mg | $1,670 | In Stock | |
| 100 mg | $2,260 | In Stock | |
| 500 mg | $4,520 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Glucocorticoid receptor agonist-1"
Corticosterone
Cited
Kendall's compound B, Corticosterone (From plants), 17-Deoxycortisol, 11β,21-Dihydroxyprogesterone
T0948L50-22-6
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stress responses in the body.
- $41
Size
QTY
CitedDexamethasone Cited
Prednisolone F, NSC 34521, MK 125, Hexadecadrol
T107650-02-2
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
ADC CytotoxinAntibacterialAntibioticAutophagyComplement SystemGlucocorticoid ReceptorIL ReceptorMitophagySARS-CoV
- $29
Size
QTY
CitedMethotrexate disodium
T80037413-34-5
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
- $34
Size
QTY
Prednisone
Dehydrocortisone
T101853-03-2
Prednisone (Dehydrocortisone) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
- $33
Size
QTY
Desonide
Tridesilon, Prednacinolone, Locapred
T1168638-94-8
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release of arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
- $30
Size
QTY
Mifepristone Cited
RU486, RU 38486, C-1073
T110284371-65-3
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
- $37
Size
QTY
CitedHydrocortisone Cited
Cortisol
T161450-23-7
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilization, and renal calcium excretion, as well as suppressing immune and inflammatory responses.
- $30
Size
QTY
CitedPrednisolone acetate
Prednisolone-21-acetate, Omnipred
T033752-21-1
Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
- $30
Size
QTY
Methotrexate Cited
WR19039, NCI-C04671, CL14377, Amethopterin
T148559-05-2
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
- $38
Size
QTY
CitedDexamethasone acetate
NSC 39471, Dexamethasone 21-acetate, Dexamethasone 17-acetate, Dexamethason acetate
T09471177-87-3
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.
- $45
Size
QTY
Prednisone acetate
Prednisone 21-acetate
T8396125-10-0
Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
- $41
Size
QTY
Nimodipine Cited
BAY-e 9736
T034366085-59-4
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
- $40
Size
QTY
CitedSelect Batch
Purity:99.51%
ee:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Glucocorticoid receptor agonist-1, a potent glucocorticoid receptor agonist, has an IC50 of 2.8 nM[1]. |
| Targets&IC50 | GR:2.8 nM (IC50) |
| In vitro | Glucocorticoid receptor agonist-1 (Compound 41) is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM.[1] |
| Molecular Weight | 569.69 |
| Formula | C35H39NO6 |
| Cas No. | 2166375-82-0 |
| Smiles | [H][C@]1(O[C@]2([H])C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO)c1ccc(Cc2cccc(N)c2)cc1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (87.77 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Glucocorticoid receptor agonist-1 | purchase Glucocorticoid receptor agonist-1 | Glucocorticoid receptor agonist-1 cost | order Glucocorticoid receptor agonist-1 | Glucocorticoid receptor agonist-1 chemical structure | Glucocorticoid receptor agonist-1 in vitro | Glucocorticoid receptor agonist-1 formula | Glucocorticoid receptor agonist-1 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.