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GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of hSK1 from an EC50 (Ca2+) value of 410 nM to 240 nM, which can be used to study neurological disorders.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $32 | In Stock | |
5 mg | $77 | In Stock | |
10 mg | $133 | In Stock | |
25 mg | $278 | In Stock | |
50 mg | $463 | In Stock | |
100 mg | $630 | In Stock | |
200 mg | $847 | In Stock |
Description | GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of hSK1 from an EC50 (Ca2+) value of 410 nM to 240 nM, which can be used to study neurological disorders. |
In vitro | GW 542573X (100 μM, 200 μM; brain slices from normal rat) was found effective in dose-dependently increasing the interval between seizure-like events.[2] |
Molecular Weight | 364.44 |
Formula | C19H28N2O5 |
Cas No. | 660846-41-3 |
Smiles | N(C(OCC1CCN(C(OC(C)(C)C)=O)CC1)=O)C2=C(OC)C=CC=C2 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (246.95 mM), Sonication is recommended. Ethanol: < 36.44 mg/mL, Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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