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hydrocotarnine is an inhibitor of Cbl.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $41 | In Stock | |
5 mg | $101 | In Stock | |
10 mg | $158 | In Stock | |
25 mg | $317 | In Stock | |
50 mg | $461 | In Stock | |
100 mg | $648 | In Stock | |
200 mg | $873 | In Stock | |
1 mL x 10 mM (in DMSO) | $94 | In Stock |
Description | hydrocotarnine is an inhibitor of Cbl. |
In vivo | In vivo, inhibition of Cbl with an analgesic drug, hydrocotarnine, increases inflammasome-mediated IL-18 secretion in the colon, and protects mice from dextran sulphate sodium-induced colitis. Together, our novel findings provide new insights into the role of the SFK-Cbl axis in suppressing NLRP3 inflammasome activation and identify a novel clinical utility of hydrocortanine for disease treatment[2]. |
Molecular Weight | 221.25 |
Formula | C12H15NO3 |
Cas No. | 550-10-7 |
Smiles | COC1=C2CN(C)CCC2=CC2=C1OCO2 |
Relative Density. | 1.1514 g/cm3 (Estimated) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/ml (248.59 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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