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Iscalimab
🥰Excellent
Catalog No. T77043Cas No. 2031153-61-2
Alias OM11-62MF, OM1162MF, CFZ-533, CFZ533
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
Iscalimab
Iscalimab
🥰Excellent
Catalog No. T77043Alias OM11-62MF, OM1162MF, CFZ-533, CFZ533Cas No. 2031153-61-2
Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $297 | In Stock | |
| 5 mg | $993 | In Stock | |
| 10 mg | $1,690 | In Stock | |
| 25 mg | $2,490 | In Stock | |
| 50 mg | $3,380 | In Stock |
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CitedSelect Batch
Concentration:9.49 mg/mL
Purity:>95%
Contact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren's syndrome. |
| In vivo | Iscalimab can prolong the rejection free survival of kidney allografts in cynomophagous monkeys. [1] In a preclinical porcine to rhesus monkey kidney xenotransplantation model, Iscalimab was administered at a load dose of 30 mg/kg on day 0, followed by weekly subcutaneous injections of 10 mg/kg for 10 weeks, then reduced to 10 mg/kg every 2 weeks, and clinically significant rejection was found. [2] |
| Alias | OM11-62MF, OM1162MF, CFZ-533, CFZ533 |
| Cas No. | 2031153-61-2 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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