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KDM2A/7A-IN-1
🥰Excellent
Catalog No. T11748Cas No. 2169272-46-0
KDM2A/7A-IN-1 is a cell-permeable and selective inhibitor of histone lysine demethylase KDM2A/7A, with potential antitumor activity for studying duodenal adenomas and ossifying fibromucoid tumors.
KDM2A/7A-IN-1
🥰Excellent
Purity: 99.59%
Catalog No. T11748Cas No. 2169272-46-0
KDM2A/7A-IN-1 is a cell-permeable and selective inhibitor of histone lysine demethylase KDM2A/7A, with potential antitumor activity for studying duodenal adenomas and ossifying fibromucoid tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $272 | In Stock | |
| 5 mg | $662 | In Stock | |
| 10 mg | $1,060 | In Stock | |
| 25 mg | $2,090 | In Stock | |
| 50 mg | $2,780 | In Stock | |
| 100 mg | $3,700 | In Stock |
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Purity:99.59%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | KDM2A/7A-IN-1 is a cell-permeable and selective inhibitor of histone lysine demethylase KDM2A/7A, with potential antitumor activity for studying duodenal adenomas and ossifying fibromucoid tumors. |
| Targets&IC50 | KDM2A:0.16 μM |
| In vitro | KDM2A/7A-IN-1 is a highly cell-permeable inhibitor of KDM2A/7A, with an IC50 of 0.16 μM. KDM2A/7A-IN-1 (0.4, 3.1, 6.2 μM) increases the level of H3K36me2 in HeLa cells with ectopic expression of catalytically active KDM2A[1]. |
| Molecular Weight | 506.68 |
| Formula | C33H38N4O |
| Cas No. | 2169272-46-0 |
| Smiles | CC(=O)N1[C@@H](c2cncc(CCCCCCCN3CCCC3)c2)[C@@](C#N)(c2ccccc12)c1ccccc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 120 mg/mL (236.84 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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