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Lifitegrast sodium
🥰Excellent
Catalog No. T3977LCas No. 1119276-80-0
Alias Xiidra sodium, SHP-606 sodium, SAR1118-023 sodium, SAR-1118-023 sodium, SAR 1118-023 sodium
Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye.
Lifitegrast sodium
🥰Excellent
Purity: 99.33%
Catalog No. T3977LAlias Xiidra sodium, SHP-606 sodium, SAR1118-023 sodium, SAR-1118-023 sodium, SAR 1118-023 sodiumCas No. 1119276-80-0
Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $29 | In Stock | |
| 5 mg | Inquiry | In Stock |
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CitedSelect Batch
Purity:99.33%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye. |
| Alias | Xiidra sodium, SHP-606 sodium, SAR1118-023 sodium, SAR-1118-023 sodium, SAR 1118-023 sodium |
| Molecular Weight | 637.46 |
| Formula | C29H23Cl2N2NaO7S |
| Cas No. | 1119276-80-0 |
| Smiles | ClC1=C2C(CN(CC2)C(C3=CC=C(C=CO4)C4=C3)=O)=CC(Cl)=C1C(N[C@H](C([O-])=O)CC5=CC(S(C)(=O)=O)=CC=C5)=O.[Na+] |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 80 mg/mL (125.50 mM), Sonication is recommended. DMSO: 80 mg/mL (125.50 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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