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Lirilumab
Catalog No. T77423Cas No. 1000676-41-4
Alias ONO-4483, IPH2102
Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-dependent NF-κB deinhibition. It can be used to study leukemia, head and neck squamous cell carcinoma (SCCHN).
Lirilumab
Lirilumab
Catalog No. T77423Alias ONO-4483, IPH2102Cas No. 1000676-41-4
Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-dependent NF-κB deinhibition. It can be used to study leukemia, head and neck squamous cell carcinoma (SCCHN).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $255 | In Stock | |
| 5 mg | $668 | In Stock | |
| 10 mg | $1,070 | In Stock | |
| 25 mg | $1,590 | In Stock | |
| 50 mg | $2,130 | In Stock | |
| 100 mg | $2,890 | In Stock |
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CitedSelect Batch
Concentration:2.26 mg/mL
Purity:98.40% (SEC-HPLC)
Contact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-dependent NF-κB deinhibition. It can be used to study leukemia, head and neck squamous cell carcinoma (SCCHN). |
| In vivo | Treatment with Lirilumab (intravenous injection; once; 15 mg/kg) enhances the survival rate of mice injected with tumor[1]. |
| Alias | ONO-4483, IPH2102 |
| Molecular Weight | 145.52 kDa |
| Cas No. | 1000676-41-4 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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