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Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 120 nM for recombinant human Lp-PLA2.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,120 | 8-10 weeks | |
50 mg | $2,780 | 8-10 weeks | |
100 mg | $3,700 | 8-10 weeks |
Description | Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 120 nM for recombinant human Lp-PLA2. |
Targets&IC50 | Lp-PLA2:120 nM |
In vitro | Lp-PLA2-IN-2 inhibits human Lp-PLA2, with an IC50 of 62 nM, in the PED6 assay. |
In vivo | Lp-PLA2-IN-2 (1 mg/kg; i.v.) treatment in rats reveals Cl, Vss, and t1/2 values of 67 mL/min/kg, 1.2 L/kg, and 0.34 hours, respectively[1]. |
Molecular Weight | 394.46 |
Formula | C19H23FN2O4S |
Cas No. | 2071636-15-0 |
Relative Density. | 1.34 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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