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Luffariellolide is a terpene compound obtained from the marine sponge Hyrtios communis. It is an inhibitor of human synoviocyte protein phospholipase A2 (HSF-PLA2) and a retinoic acid receptor (RAR) agonist. Luffariellolide inhibits hypoxia (1% O2)-induced HIF-1 activation and inhibits cell growth.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 441 € | 35 days |
Description | Luffariellolide is a terpene compound obtained from the marine sponge Hyrtios communis. It is an inhibitor of human synoviocyte protein phospholipase A2 (HSF-PLA2) and a retinoic acid receptor (RAR) agonist. Luffariellolide inhibits hypoxia (1% O2)-induced HIF-1 activation and inhibits cell growth. |
Targets&IC50 | Bee venom phospholipase A2:0.23 μM |
In vitro | Luffariellolide inhibited in vitro hydrolysis of phosphatidyl choline by purified bee venom phospholipase A2 (IC50 = 0.23 μM). [1] |
Molecular Weight | 386.57 |
Formula | C25H38O3 |
Cas No. | 111149-87-2 |
Smiles | C(C/C(=C/CC/C(=C/CCC1=CC(=O)OC1O)/C)/C)C=2C(C)(C)CCCC2C |
Relative Density. | 1.31g/cm3 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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