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ME1111

ME1111
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Purity:100%
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ME1111

Catalog No. T16033Cas No. 1391758-52-3
ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes. Notably proficient in penetrating human nails, it is utilized in onychomycosis research.
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Pack SizePriceAvailabilityQuantity
1 mg$118In Stock
5 mg$291In Stock
10 mg$432In Stock
25 mg$715In Stock
50 mg$987In Stock
100 mg$1,360In Stock
500 mg$2,730In Stock
1 mL x 10 mM (in DMSO)$267In Stock
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Product Introduction

Bioactivity
Description
ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes. Notably proficient in penetrating human nails, it is utilized in onychomycosis research.
In vitro
ME1111 (0.125, 0.0625 μg/mL; 4, 8, 12 h) inhibits T. mentagrophytes TIMM 2789 (MICs: 0.5 μg/mL and 0.25 μg/mL in RPMI 1640 medium and SDB, respectively).[2]
ME1111 strongly inhibits the succinate-2,6-dichlorophenolindophenol reductase reaction in Trichophyton rubrum and T. mentagrophytes (IC50: 0.029 μg/mL, 0.025 μg/mL) but only shows moderate inhibition of the same reaction in human cell lines.[2]
Chemical Properties
Molecular Weight202.25
FormulaC12H14N2O
Cas No.1391758-52-3
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 90.0 mg/mL (445.0 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.9444 mL24.7219 mL49.4438 mL247.2188 mL
5 mM0.9889 mL4.9444 mL9.8888 mL49.4438 mL
10 mM0.4944 mL2.4722 mL4.9444 mL24.7219 mL
20 mM0.2472 mL1.2361 mL2.4722 mL12.3609 mL
50 mM0.0989 mL0.4944 mL0.9889 mL4.9444 mL
100 mM0.0494 mL0.2472 mL0.4944 mL2.4722 mL

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