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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $247 | In Stock | |
50 mg | $393 | In Stock | |
100 mg | $593 | In Stock | |
500 mg | $1,280 | In Stock | |
1 mL x 10 mM (in DMSO) | $79 | In Stock |
Description | ML289 (VU0463597) is a potent, selective, and CNS-penetrant negative allosteric modulator of mGlu3 (IC50=0.66 μM), with over 15-fold selectivity compared to mGlu2 and no activity against mGlu5. |
Targets&IC50 | mGluR3:0.66 μM (IC50) |
In vitro | ML289 (VU0463597) is a central nervous system (CNS)-penetrant probe that functions as a negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3)[1]. |
Alias | VU0463597, ML 289 |
Molecular Weight | 349.42 |
Formula | C22H23NO3 |
Cas No. | 1382481-79-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 225 mg/mL (643.9 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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