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ML401

Catalog No. T8234Cas No. 1597489-14-9

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .

ML401

ML401

Purity: 99.13%
Catalog No. T8234Cas No. 1597489-14-9
ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
Pack SizePriceAvailabilityQuantity
1 mg$135In Stock
2 mg$159In Stock
5 mg$197In Stock
10 mg$322In Stock
25 mg$513In Stock
50 mg$689In Stock
100 mg$892In Stock
500 mg$1,820In Stock
1 mL x 10 mM (in DMSO)$217In Stock
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Purity:99.13%
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Product Introduction

Bioactivity
Description
ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
Targets&IC50
EBI2/GPR183:1.03 nM
Chemical Properties
Molecular Weight419.74
FormulaC20H20BrClN2O
Cas No.1597489-14-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (23.82 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3824 mL11.9121 mL23.8243 mL119.1214 mL
5 mM0.4765 mL2.3824 mL4.7649 mL23.8243 mL
10 mM0.2382 mL1.1912 mL2.3824 mL11.9121 mL
20 mM0.1191 mL0.5956 mL1.1912 mL5.9561 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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