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Morolic acid
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Catalog No. TN4584Cas No. 559-68-2
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Morolic acid exhibits pronounced radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl radical and is a potent inhibitor of neutrophil elastase and cyclooxygenase-1 and -2 in vitro. Morolic acid has anti- inflammatory activity, it can inhibit leukotriene B4 production in rat polymorphonuclear leukocytes stimulated with calcium ionophore A 23187. Morolic acid exhibits promising anti-HIV activity, it also exhibits moderate inhibitory activity against glycogen phosphorylase.
Morolic acid
😃Good
Catalog No. TN4584Cas No. 559-68-2
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Morolic acid exhibits pronounced radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl radical and is a potent inhibitor of neutrophil elastase and cyclooxygenase-1 and -2 in vitro. Morolic acid has anti- inflammatory activity, it can inhibit leukotriene B4 production in rat polymorphonuclear leukocytes stimulated with calcium ionophore A 23187. Morolic acid exhibits promising anti-HIV activity, it also exhibits moderate inhibitory activity against glycogen phosphorylase.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $540 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $550 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro |
| Molecular Weight | 456.7 |
| Formula | C30H48O3 |
| Cas No. | 559-68-2 |
| Relative Density. | 1.10 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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