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Mps1-IN-2 is a potent, selective, and ATP-competitive inhibitor of both Mps1 and Plk1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $34 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $98 | In Stock |
Description | Mps1-IN-2 is a potent, selective, and ATP-competitive inhibitor of both Mps1 and Plk1. |
Targets&IC50 | Mps1:145 nM |
Kinase Assay | mTOR activity is assayed using LanthaScreen Kinase kit reagents. PI(3)K α, β, γ and δ activity are assayed using the PI(3)K HTRF assay kit. The concentration of INK128 necessary to achieve inhibition of enzyme activity by 50% (IC50) is calculated using concentrations ranging from 20 μM to 0.1 nM (12-point curve). IC50?values are determined using a nonlinear regression model. |
Molecular Weight | 480.6 |
Formula | C26H36N6O3 |
Cas No. | 1228817-38-6 |
Smiles | CCOc1cc(ccc1Nc1ncc2N(C)C(=O)CCN(C3CCCC3)c2n1)N1CCC(O)CC1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 14.3 mg/mL (30 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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