Neuraminidase-IN-13 (Compound 10), a neuraminidase inhibitor exhibiting antiviral activity, demonstrates significant inhibition of NDV infection in Vero cells with minimal cytotoxicity by impeding the release of viral particles from infected cells [1].

Neuraminidase-IN-13 inhibits plaque formation in the NDV La Sota strain with an IC50 of 0.06 µM [1]. It also suppresses viral replication with an IC50 of 0.04 µM [1] and demonstrates no cytotoxicity on cells, with a CC50 value greater than 2500 µM [1]. Furthermore, Neuraminidase-IN-13 impedes viral attachment to Vero cells, having an IC50 of 4 µM [1], and obstructs the release of the virus from Vero cells with an IC50 of 0.09 µM [1].