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NLRP3-IN-11
🥰Excellent
Catalog No. T61132Cas No. 2769040-91-5
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
NLRP3-IN-11
🥰Excellent
Purity: 100%
Catalog No. T61132Cas No. 2769040-91-5
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $108 | In Stock | |
| 10 mg | $158 | In Stock | |
| 25 mg | $266 | In Stock | |
| 50 mg | $395 | In Stock | |
| 100 mg | $587 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism. |
| Targets&IC50 | NLRP3:<0.3 μM |
| In vitro | NLRP3-IN-11 exhibits biological activity with an IC50 value of <0.3 μM in a human PBMC NLRP3 assay [1]. |
| Molecular Weight | 344.8 |
| Formula | C17H17ClN4O2 |
| Cas No. | 2769040-91-5 |
| Smiles | N(CC(C)(C)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CN=C2 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (290.02 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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