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ADS032

🥰Excellent
TargetMol
Catalog No. T79906Cas No. 2757333-37-0
Alias BT-032

ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.

ADS032

ADS032

🥰Excellent
TargetMol
Purity: 99.33%
Catalog No. T79906Alias BT-032Cas No. 2757333-37-0
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.
Pack SizePriceAvailabilityQuantity
1 mg$42In Stock
5 mg$98In Stock
10 mg$168In Stock
25 mg$338In Stock
50 mg$579In Stock
100 mg$928In Stock
1 mL x 10 mM (in DMSO)$108In Stock
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Purity:99.33%
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Product Introduction

Bioactivity
Description
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.
AliasBT-032
Chemical Properties
Molecular Weight403.54
FormulaC22H29NO4S
Cas No.2757333-37-0
SmilesO=C(O)CCCC1=CC=C(C=C1)C=2C=CC(=CC2)S(=O)(=O)N(CCC)CCC
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
Ethanol: 5 mg/mL (12.39 mM), Sonication and heating are recommended.
DMSO: 80 mg/mL (198.25 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.4781 mL12.3903 mL24.7807 mL123.9035 mL
5 mM0.4956 mL2.4781 mL4.9561 mL24.7807 mL
10 mM0.2478 mL1.2390 mL2.4781 mL12.3903 mL
DMSO
1mg5mg10mg50mg
20 mM0.1239 mL0.6195 mL1.2390 mL6.1952 mL
50 mM0.0496 mL0.2478 mL0.4956 mL2.4781 mL
100 mM0.0248 mL0.1239 mL0.2478 mL1.2390 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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