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NVS-CECR2-1
🥰Excellent
Catalog No. T37151Cas No. 1992047-61-6
NVS-CECR2-1 is a selective cat eye syndrome chromosome region candidate 2 (CECR2) inhibitor with antitumor activity and inhibits chromatin binding of CECR2 BRD. NVS-CECR2-1 is cytotoxic and can induce apoptosis.
NVS-CECR2-1
🥰Excellent
Purity: 98.68%
Catalog No. T37151Cas No. 1992047-61-6
NVS-CECR2-1 is a selective cat eye syndrome chromosome region candidate 2 (CECR2) inhibitor with antitumor activity and inhibits chromatin binding of CECR2 BRD. NVS-CECR2-1 is cytotoxic and can induce apoptosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $199 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | NVS-CECR2-1 is a selective cat eye syndrome chromosome region candidate 2 (CECR2) inhibitor with antitumor activity and inhibits chromatin binding of CECR2 BRD. NVS-CECR2-1 is cytotoxic and can induce apoptosis. |
| Targets&IC50 | SW48 cells:0.64 μM |
| In vitro | The cells were treated with increasing concentrations of NVS-CECR2-1 up to 4 μM and their clonogenic ability was evaluated afer ten days by colony formation assay. NVS-CECR2-1 inhibited the clonogenic ability of SW48 cells in a dose dependent manner and its IC50 value was estimated to be 0.64 μM. [1] |
| Molecular Weight | 495.68 |
| Formula | C27H37N5O2S |
| Cas No. | 1992047-61-6 |
| Smiles | O=S(=O)(C1=NC(=CC(=N1)C2=CC=C3C(C=CN3C4CC(NC(C)(C)C4)(C)C)=C2)NC5CC5)CCC |
Storage & Solubility Information
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (100.87 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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