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OR-1896

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Purity:99.51%

ee:98.65%

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COA CSFC HNMR HPLC LCMS ORP

OR-1896

Catalog No. T12315Cas No. 220246-81-1

OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood vessels through activation of ATP-sensitive (KATP) and other potassium channels.OR-1896 can be used to study heart failure and vascular dysfunction. OR-1896 can be used to study heart failure and vascular dysfunction.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$93	In Stock
2 mg	$137	In Stock
5 mg	$228	In Stock
10 mg	$413	In Stock
25 mg	$892	In Stock
50 mg	$1,220	In Stock
100 mg	$1,650	In Stock
1 mL x 10 mM (in DMSO)	$253	In Stock

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Product Introduction

Bioactivity

Description

In vitro

OR-1896 can achieve vasodilation by activating ATP-sensitive potassium channels in smooth muscle cells[1].

Chemical Properties

Molecular Weight	245.28
Formula	C13H15N3O2
Cas No.	220246-81-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (203.85 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0770 mL	20.3849 mL	40.7697 mL	203.8487 mL
5 mM	0.8154 mL	4.0770 mL	8.1539 mL	40.7697 mL
10 mM	0.4077 mL	2.0385 mL	4.0770 mL	20.3849 mL
20 mM	0.2038 mL	1.0192 mL	2.0385 mL	10.1924 mL
50 mM	0.0815 mL	0.4077 mL	0.8154 mL	4.0770 mL
100 mM	0.0408 mL	0.2038 mL	0.4077 mL	2.0385 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc