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PA452
🥰Excellent
Catalog No. T16425Cas No. 457657-34-0
PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development.
PA452
🥰Excellent
Purity: 96.76%
Catalog No. T16425Cas No. 457657-34-0
PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 79 € | In Stock | |
| 5 mg | 249 € | In Stock | |
| 10 mg | 401 € | In Stock | |
| 25 mg | 657 € | In Stock | |
| 50 mg | 936 € | In Stock | |
| 100 mg | 1.282 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 273 € | In Stock |
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Purity:96.76%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development. |
| In vitro | PA452 suppresses the Troglitazone (TZ)-induced CK13 expression. In normal human urothelial (NHU) cells, PA452 (0.01-1 μM) inhibits retinoic X receptor[2]. |
| Molecular Weight | 439.59 |
| Formula | C26H37N3O3 |
| Cas No. | 457657-34-0 |
| Smiles | CCCCCCOc1cc2c(cc1N(C)c1ncc(cn1)C(O)=O)C(C)(C)CCC2(C)C |
| Relative Density. | 1.090 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 4.4 mg/mL (10.01 mM), Sonication and heating are recommended. DMSO: 36 mg/mL (81.9 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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