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PAPA NONOate

🥰Excellent
Catalog No. T74048Cas No. 146672-58-4

PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders.

PAPA NONOate

PAPA NONOate

🥰Excellent
Purity: 98%
Catalog No. T74048Cas No. 146672-58-4
PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders.
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2 mg$49In Stock
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Purity:98%
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Product Introduction

Bioactivity
Description
PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders.
In vitro
Incubation with PAPA NONOate (50 μM) for 12 hours significantly reduced the increase in caspase-3-like activity induced by caspase-3 overexpression by 70%[1].
In vivo
In phosphate-buffered saline, treatment of rat dorsal skin wounds with 100 μM PAPA NONOate resulted in improved wound healing rates in the treated group[2].
Chemical Properties
Molecular Weight176.22
FormulaC6H16N4O2
Cas No.146672-58-4
SmilesO=NN(O)N(CCC)CCCN
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 30 mg/mL (170.25 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.6747 mL28.3736 mL56.7472 mL283.7362 mL
5 mM1.1349 mL5.6747 mL11.3494 mL56.7472 mL
10 mM0.5675 mL2.8374 mL5.6747 mL28.3736 mL
20 mM0.2837 mL1.4187 mL2.8374 mL14.1868 mL
50 mM0.1135 mL0.5675 mL1.1349 mL5.6747 mL
100 mM0.0567 mL0.2837 mL0.5675 mL2.8374 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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