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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $139 | In Stock | |
5 mg | $347 | In Stock | |
10 mg | $562 | In Stock | |
25 mg | $1,060 | In Stock | |
50 mg | $1,630 | In Stock | |
100 mg | $2,280 | In Stock | |
1 mL x 10 mM (in DMSO) | $522 | In Stock |
Description | PC945 (Opelconazole) is a potent broad-spectrum antifungal compound with inhibitory effect on fumonisinol 14α-demethylase (CYP51A/CYP51B), which can be used in the study of fungal infections of the lungs. |
In vitro | Designed for administration via inhalation, PC945 is a triazole antifungal[1]. PC945 demonstrates the most potent antifungal activity against the azole-susceptible strain NCPF2010, with a MIC value of 0.063 µg/mL[1]. |
In vivo | Substantially inhibiting the incidence of rolling behavior, PC945 (0.56-14 μg/mouse; intranasal; daily for 7 days) is observed[2]. |
Alias | Opelconazole |
Molecular Weight | 682.73 |
Formula | C38H37F3N6O3 |
Cas No. | 1931946-73-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (117.18 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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