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RBN-3143
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RBN-3143
Catalog No. T67844Cas No. 2360853-16-1
RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines. RBN-3143 exhibits research potential of lung inflammation.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $87 | In Stock | |
| 5 mg | $213 | In Stock | |
| 10 mg | $313 | In Stock | |
| 25 mg | $533 | In Stock | |
| 50 mg | $768 | In Stock | |
| 100 mg | $1,080 | In Stock | |
| 500 mg | $2,160 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $235 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines. RBN-3143 exhibits research potential of lung inflammation. |
| In vivo | RBN-3143 (5 μg; Intranasal administration) can improve the steroid resistant asthma mouse model [1]. |
| Molecular Weight | 449.54 |
| Formula | C22H28FN3O4S |
| Cas No. | 2360853-16-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
| Solubility Information | DMSO: 11.2 mg/mL (25.0 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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