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S-Allylmercaptocysteine HCl（2281-22-3 Free base）
🥰Excellent
Catalog No. T74414L
Alias S-Allylmercaptocysteine HCl（2281-22-3 Free base）
S-Allylmercaptocysteine HCl is an organosulfur compound isolated from aged garlic with anti-inflammatory, antioxidant, anticancer, and antitumor activities.S-Allylmercaptocysteine HCl inhibits inflammation in COPD and targets Nrf2 in osteoarthritis therapy through the NOX4/NF-kappaB pathway. Targeting Nrf2.
S-Allylmercaptocysteine HCl（2281-22-3 Free base）
S-Allylmercaptocysteine HCl（2281-22-3 Free base）
🥰Excellent
Purity: 100%
Catalog No. T74414LAlias S-Allylmercaptocysteine HCl（2281-22-3 Free base）
S-Allylmercaptocysteine HCl is an organosulfur compound isolated from aged garlic with anti-inflammatory, antioxidant, anticancer, and antitumor activities.S-Allylmercaptocysteine HCl inhibits inflammation in COPD and targets Nrf2 in osteoarthritis therapy through the NOX4/NF-kappaB pathway. Targeting Nrf2.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $68 | In Stock | |
| 5 mg | $150 | In Stock | |
| 10 mg | $240 | In Stock | |
| 25 mg | $480 | In Stock | |
| 50 mg | $790 | In Stock | |
| 100 mg | $1,286 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | S-Allylmercaptocysteine HCl is an organosulfur compound isolated from aged garlic with anti-inflammatory, antioxidant, anticancer, and antitumor activities.S-Allylmercaptocysteine HCl inhibits inflammation in COPD and targets Nrf2 in osteoarthritis therapy through the NOX4/NF-kappaB pathway. Targeting Nrf2. |
| In vitro | S-Allylmercaptocysteine HCl induced apoptosis in SW620, SW480, and Caco-2 cells, and activated caspase 3 and cleaved PARP1 were found in cells treated with S-Allylmercaptocysteine HCl, whereas they were not found in untreated control cells activated PARP1 and caspase 3. [1] S-Allylmercaptocysteine HCl attenuated cisplatin-induced nephrotoxicity by inhibiting apoptosis, oxidative stress and inflammation. [2] |
| In vivo | Oral administration of 25 and 50 mg/kg S-Allylmercaptocysteine HCl ,significantly ameliorated the pathology of BLM-induced pulmonary fibrosis in mice, showing antifibrotic effects by increasing antioxidants such as heme oxygenase-1 (HO-1), glutathione (GSH) and superoxide dismutase (SOD), and decreasing hydroxyproline (HYP). S-Allylmercaptocysteine HCl reduced inflammatory cell infiltration in bronchoalveolar lavage fluid (BALF) and decreased pro-inflammatory cytokine levels in BALF.[3] |
| Alias | S-Allylmercaptocysteine HCl（2281-22-3 Free base） |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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