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S-Allylmercaptocysteine
🥰Excellent
Catalog No. T74414Cas No. 2281-22-3
S-Allylmercaptocysteine (SAMC) is an organic sulfur compound extracted from garlic, with anti-cancer, anti-inflammatory, and antioxidant properties. It protects against hepatocellular damage, improves alcoholic liver disease by modulating insulin receptor signaling, and enhances anti-tumor immunity by inhibiting PD-L1 expression.
S-Allylmercaptocysteine
🥰Excellent
Catalog No. T74414Cas No. 2281-22-3
S-Allylmercaptocysteine (SAMC) is an organic sulfur compound extracted from garlic, with anti-cancer, anti-inflammatory, and antioxidant properties. It protects against hepatocellular damage, improves alcoholic liver disease by modulating insulin receptor signaling, and enhances anti-tumor immunity by inhibiting PD-L1 expression.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $228 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | S-Allylmercaptocysteine (SAMC) is an organic sulfur compound extracted from garlic, with anti-cancer, anti-inflammatory, and antioxidant properties. It protects against hepatocellular damage, improves alcoholic liver disease by modulating insulin receptor signaling, and enhances anti-tumor immunity by inhibiting PD-L1 expression. |
| In vitro | S-Allylmercaptocysteine (250 μmol/L, 24h) can improve chemical damage caused by chemical induction of normal mouse liver cell line AML-12, EC50 = 178.4 μmol/L. [1] |
| In vivo | S-Allylmercaptocysteine (300 mg/kg, administered one day at a time, 90 days by gavage) effectively improved ALD-induced weight loss, steatosis, insulin resistance, and inflammation without affecting the health status of control mice. [1] S-Allylmercaptocysteine inhibits tumor development and progression by promoting the infiltration of CD8 T cells and NK cells, reducing the frequency of immunosuppressive Treg cells in tumor tissues, and enhancing systemic immune function. [2] |
| Molecular Weight | 193.29 |
| Formula | C6H11NO2S2 |
| Cas No. | 2281-22-3 |
| Smiles | [C@H](CSSCC=C)(C(O)=O)N |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: < 1 mg/mL (insoluble or slightly soluble) H2O: 1.00 mg/mL (5.17 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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