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Sanguisorbigenin

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Purity:98.11%

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COA HNMR HPLC

Sanguisorbigenin

Catalog No. TN4943Cas No. 6812-98-2

Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).

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Pack Size	Price	Availability
1 mg	$313	In Stock
5 mg	$663	In Stock
10 mg	$995	In Stock
25 mg	$1,470	In Stock
50 mg	$1,990	In Stock
100 mg	$2,680	In Stock
1 mL x 10 mM (in DMSO)	$763	In Stock

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Product Introduction

Bioactivity

Description	Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).
In vitro	Treatment of Sanguisorbigenin with sub-MIC concentrations (1.56-6.25 μg/mL) significantly inhibited the expression of blaR1, mecA, and blaZ in MRSA dose-dependently. The gene expression of mecA is remarkably reduced after the treatment of Sanguisorbigenin. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decreasing PBP2a expression[1].
Alias	Tomentosolic acid, 3β-Hydroxyurs-12,19-dien-28-oic acid, 19-Dehydroursolic acid, Ursa-12,19-dien-28-oic acid

Chemical Properties

Molecular Weight	454.68
Formula	C30H46O3
Cas No.	6812-98-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (127.48 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1993 mL	10.9967 mL	21.9935 mL	109.9674 mL
5 mM	0.4399 mL	2.1993 mL	4.3987 mL	21.9935 mL
10 mM	0.2199 mL	1.0997 mL	2.1993 mL	10.9967 mL
20 mM	0.1100 mL	0.5498 mL	1.0997 mL	5.4984 mL
50 mM	0.0440 mL	0.2199 mL	0.4399 mL	2.1993 mL
100 mM	0.0220 mL	0.1100 mL	0.2199 mL	1.0997 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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