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sEH inhibitor-7

Catalog No. T60358Cas No. 340221-20-7

sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules.

sEH inhibitor-7

sEH inhibitor-7

Purity: 99.56%
Catalog No. T60358Cas No. 340221-20-7
sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules.
Pack SizePriceAvailabilityQuantity
5 mg$47In Stock
10 mg$80In Stock
25 mg$163In Stock
50 mg$247In Stock
100 mg$372In Stock
500 mg$869In Stock
1 mL x 10 mM (in DMSO)$52In Stock
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Purity:99.56%
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Product Introduction

Bioactivity
Description
sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules.
Targets&IC50
sEH (human):6.2 μM, sEH (mouse):0.15 μM
In vitro
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation.[1]
Chemical Properties
Molecular Weight247.33
FormulaC15H21NO2
Cas No.340221-20-7
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (363.9 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0432 mL20.2159 mL40.4318 mL202.1591 mL
5 mM0.8086 mL4.0432 mL8.0864 mL40.4318 mL
10 mM0.4043 mL2.0216 mL4.0432 mL20.2159 mL
20 mM0.2022 mL1.0108 mL2.0216 mL10.1080 mL
50 mM0.0809 mL0.4043 mL0.8086 mL4.0432 mL
100 mM0.0404 mL0.2022 mL0.4043 mL2.0216 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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