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EC5026

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Purity:99.87%

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COA HPLC HNMR

EC5026

Catalog No. T11147Cas No. 1809885-32-2

EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.

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Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$46	In Stock
10 mg	$75	In Stock
25 mg	$124	In Stock
50 mg	$221	In Stock
100 mg	$329	In Stock
1 mL x 10 mM (in DMSO)	$52	In Stock

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Product Introduction

Bioactivity

Description	EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
In vivo	EC5026 (BPN-19186) is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids.?Inhibition of sEH treats pain by stabilizing natural analgesic and anti-inflammatory mediators.?sEH inhibitors developed by EicOsis have already shown efficacy for treating pain with no apparent adverse or addictive effects in laboratory animals and relieving naturally occurring pain in dogs, cats and horses.
Alias	BPN-19186

Chemical Properties

Molecular Weight	405.39
Formula	C18H23F4N3O3
Cas No.	1809885-32-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 250 mg/mL (616.69 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4668 mL	12.3338 mL	24.6676 mL	123.3380 mL
5 mM	0.4934 mL	2.4668 mL	4.9335 mL	24.6676 mL
10 mM	0.2467 mL	1.2334 mL	2.4668 mL	12.3338 mL
20 mM	0.1233 mL	0.6167 mL	1.2334 mL	6.1669 mL
50 mM	0.0493 mL	0.2467 mL	0.4934 mL	2.4668 mL
100 mM	0.0247 mL	0.1233 mL	0.2467 mL	1.2334 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc