Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $447 | 6-8 weeks | |
25 mg | $1,530 | 6-8 weeks | |
50 mg | $1,990 | 6-8 weeks | |
100 mg | $3,280 | 6-8 weeks | |
1 mL x 10 mM (in DMSO) | $430 | 6-8 weeks |
Description | Soraprazan is a reversible, and fast-acting gastric H+/K+ ATPase inhibitor. |
In vitro | Soraprazan is a potent gastric H,K-ATPase inhibitor(IC50 :0.1 μM) when measured in ion-leaky vesicles in the presence of 1 mM potassium. Soraprazan also effectively inhibits dibutyryl cAMP-stimulated [14C]AP accumulation in isolated gastric glands(IC50 of 0.19 μM )(0.09-0.40 μM geometric mean from n=6 with 95% confidence limits). In ion-leaky vesicles, soraprazan is a potent k-competitive the H,K-ATPase inhibitor(Ki of 6.4 nM). Soraprazan binds to the H,K-ATPase in ion-leaky vesicles with a Kd of 26.4 nM and a Bmax of 2.89 nmol/mg. |
Alias | BYK61359 |
Molecular Weight | 367.44 |
Formula | C21H25N3O3 |
Cas No. | 261944-46-1 |
Storage | ||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 150 mg/mL (408.23 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.