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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $77 | In Stock | |
5 mg | $189 | In Stock | |
10 mg | $287 | In Stock | |
25 mg | $578 | In Stock | |
50 mg | $833 | In Stock | |
100 mg | $1,150 | In Stock | |
500 mg | $2,290 | In Stock | |
1 mL x 10 mM (in DMSO) | $239 | In Stock |
Description | SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element. |
In vitro | SR11237 is effective at transactivating a chloramphenicol acetyltransferase reporter gene through RXRs but not retinoic acid receptors in COS-1 cells[2]. |
In vivo | In Sprague-Dawley rats, SR11237 (BMS-649) (25 mg/kg; i.p.) Caused disturbed ossification and bone morphology in rats, including premature growth plate closure and infiltration of ossified tissue through the central epiphysis[3]. |
Alias | SR 11237 |
Molecular Weight | 380.48 |
Formula | C24H28O4 |
Cas No. | 146670-40-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||
Solubility Information | Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 4 mg/mL (10.51 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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