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STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $45 | In Stock | |
25 mg | $85 | In Stock | |
50 mg | $134 | In Stock | |
100 mg | $207 | In Stock | |
200 mg | $310 | In Stock |
Description | STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. |
In vitro | C-171 binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM[1]. |
Alias | C-171 |
Molecular Weight | 316.35 |
Formula | C17H20N2O4 |
Cas No. | 2244881-69-2 |
Smiles | CCCCCCc1ccc(NC(=O)c2ccc(o2)[N+]([O-])=O)cc1 |
Relative Density. | 1.208 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 3.16 mg/mL (10 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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