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STING-IN-3

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Catalog No. T9029Cas No. 2244881-69-2
Alias C-171

STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.

STING-IN-3

STING-IN-3

🥰Excellent
Purity: 98.15%
Catalog No. T9029Alias C-171Cas No. 2244881-69-2
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Pack SizePriceAvailabilityQuantity
10 mg$45In Stock
25 mg$85In Stock
50 mg$134In Stock
100 mg$207In Stock
200 mg$310In Stock
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Purity:98.15%
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Product Introduction

Bioactivity
Description
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
In vitro
C-171 binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM[1].
AliasC-171
Chemical Properties
Molecular Weight316.35
FormulaC17H20N2O4
Cas No.2244881-69-2
SmilesCCCCCCc1ccc(NC(=O)c2ccc(o2)[N+]([O-])=O)cc1
Relative Density.1.208 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3.16 mg/mL (10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1611 mL15.8053 mL31.6106 mL158.0528 mL
5 mM0.6322 mL3.1611 mL6.3221 mL31.6106 mL
10 mM0.3161 mL1.5805 mL3.1611 mL15.8053 mL

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