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sulfo-DGN462 sodium
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sulfo-DGN462 sodium
Catalog No. T38823Cas No. 1401203-09-5
Sulfo-DGN462 sodium undergoes degradation to DGN462 when subjected to culture medium and plasma. DGN462, a highly effective DNA-alkylating agent, exhibits anti-tumor properties that are particularly active against acute myeloid leukemia (AML).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | Backorder |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sulfo-DGN462 sodium undergoes degradation to DGN462 when subjected to culture medium and plasma. DGN462, a highly effective DNA-alkylating agent, exhibits anti-tumor properties that are particularly active against acute myeloid leukemia (AML). |
| In vitro | DGN462 serves as a cytotoxic agent in antibody-drug conjugates (ADCs), demonstrating its utility in targeted cancer therapy. It belongs to the class of DNA-alkylating indolinobenzodiazepine pseudodimers (IGNs), indicating its mechanism of action at the molecular level[1]. |
| Alias | sulfo-DGN462 sodium |
| Molecular Weight | 1047.2 |
| Formula | C53H61N5NaO12S2 |
| Cas No. | 1401203-09-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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