sulfo dgn462 sodium

Sulfo-DGN462 sodium undergoes degradation to DGN462 when subjected to culture medium and plasma. DGN462, a highly effective DNA-alkylating agent, exhibits anti-tumor properties that are particularly active against acute myeloid leukemia (AML).

S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.

Sulfo-SIAB sodium is a non-cleavable monovalent bifunctional linker.

Sulfo-NHS-LC-Biotin sodium is an amine-reactive biotinylation reagent used for antibody labeling.

Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent that combines N-hydroxysuccinimide ester and maleimide groups, enabling the covalent conjugation of molecules possessing (amine) and (sulfhydryl) functionalities.

DBCO-Sulfo-NHS ester sodium is a cleavable linker primarily used in the synthesis of antibody-drug conjugates (ADCs)[1].

Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl ether-based PROTAC linker used for PROTAC synthesis [1].

Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable it to specifically react with primary amines and sulfhydryl groups, respectively.

6-O-Sulfo-β-cyclodextrin is a sulfated cyclodextrin.1It has been used for the chiral separation of nadolol racemates by capillary electrophoresis. 1.Wang, F., Dowling, T., Bicker, G., et al.Electrophoretic chiral separation of pharmaceutical compounds with multiple stereogenic centers in charged cyclodextrin mediaJ. Sep. Sci.24(5)378-384(2001)

Sulfo-SPDB-DGN462 is an agent-linker conjugate utilized for Antibody-Drug Conjugates (ADCs), featuring the potent DNA-alkylating agent DGN462 known for its anti-tumor properties, including efficacy against acute myeloid leukemia (AML), and is conjugated via the cleavable Sulfo-SPDB linker.

ICG-Sulfo-OSu sodium is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system [in cells].