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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $280 | In Stock | |
5 mg | $689 | In Stock | |
10 mg | $983 | In Stock | |
25 mg | $1,460 | In Stock | |
50 mg | $1,970 | In Stock | |
100 mg | $2,650 | In Stock |
Description | Tanimilast (CHF-6001) is a novel, potent and selective phosphodiesterase 4 inhibitor with an IC 50 value of 0.026 ± 0.006 nM.Tanimilast has potent anti-inflammatory activity and is indicated for topical use in the lungs.Tanimilast was used in the study of obstructive lung disease. |
In vitro | Methacholine-induced protein expression of smooth muscle-myosin was fully inhibited by CHF-6001 (0.3-100 nM; Guinea pig precision-cut lung slices). CHF-6001 did not affect airway closure and had limited effects on TGF-β1-induced remodeling, but rather, it inhibited methacholine-induced TGF-β release.[2] |
Alias | CHF-6001 |
Molecular Weight | 687.54 |
Formula | C30H30Cl2F2N2O8S |
Cas No. | 1239278-59-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (72.72 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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