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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $152 | In Stock | |
5 mg | $373 | In Stock | |
10 mg | $473 | In Stock | |
25 mg | $777 | In Stock | |
50 mg | $1,090 | In Stock | |
100 mg | $1,460 | In Stock | |
500 mg | $2,930 | In Stock | |
1 mL x 10 mM (in DMSO) | $397 | In Stock |
Description | TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors. |
In vitro | TBOPP as a selective inhibitor of DOCK1. TBOPP dampened DOCK1-mediated invasion, macropinocytosis, and survival under the condition of glutamine deprivation without impairing the biological functions of the closely related DOCK2 and DOCK5 proteins. |
In vivo | TBOPP treatment suppressed cancer metastasis and growth in vivo in mice. |
Molecular Weight | 490.49 |
Formula | C24H21F3N2O4S |
Cas No. | 1996629-79-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 120 mg/mL (244.65 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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