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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Telomerase-IN-4 is a potent telomerase inhibitor with antiproliferative properties and apoptosis-inducing effects [1]. |
In vitro | Telomerase-IN-4 (compound 8e; 0.1-100 μg/mL; 72 h) demonstrates antitumor activity against MCF-7 and A549 cancer cell lines, with IC50 values of 9.47 μg/mL and 17.09 μg/mL, respectively [1]. At 9.467 μg/mL over 48 hours, it induces S phase cell cycle arrest and apoptosis in MCF-7 cells [1]. |
In vivo | Telomerase-IN-4, administered intraperitoneally at a dose of 5 mg/kg three times weekly over two weeks, exhibited anticancer activity by inhibiting tumor growth in albino female Swiss mice [1]. |
Molecular Weight | 406.52 |
Formula | C21H18N4OS2 |
Cas No. | 2892295-10-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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