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Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | In Stock | |
10 mg | $40 | In Stock | |
25 mg | $69 | In Stock |
Description | Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism. |
In vitro | In Adh5-/- DT40 cells, Tetrahydrofolic acid (0-200 µM; 3 days) resulted in a rapid drop in cell viability[1]. |
In vivo | In Adh5-/- mice, Tetrahydrofolic acid (62.5 mg/kg; intraperitoneal injection; daily) resulted in disrupted hematopoiesis, increased phosphorylation of Ser139-H2AX, and decreased survival of hematopoietic stem and progenitor cells (HSPCs)[1]. |
Alias | th-folate, Tetrahydropteroylglutamic acid, folate-H4, 5,6,7,8-tetrahydrofolic acid |
Molecular Weight | 445.43 |
Formula | C19H23N7O6 |
Cas No. | 135-16-0 |
Smiles | Nc1nc2NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)Nc2c(=O)[nH]1 |
Relative Density. | 1.7g/cm3 |
Storage | store under nitrogen,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | DMSO: 1 mg/mL (2.25 mM), Sonication is recommended. H2O: 1 mg/mL (2.25 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO/H2O
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