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TG2-179-1
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Catalog No. T83855Cas No. 1135023-19-6
TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity. TG2-179-1 exhibits potent cytotoxic activity against colon cancer cells and induces apoptosis. TG2-179-1 can be used in colon cancer research. TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity.
TG2-179-1
😃Good
Catalog No. T83855Cas No. 1135023-19-6
TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity. TG2-179-1 exhibits potent cytotoxic activity against colon cancer cells and induces apoptosis. TG2-179-1 can be used in colon cancer research. TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $198 | 35 days | |
| 5 mg | $791 | 35 days | |
| 10 mg | $1,410 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity. TG2-179-1 exhibits potent cytotoxic activity against colon cancer cells and induces apoptosis. TG2-179-1 can be used in colon cancer research. TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity. |
| Molecular Weight | 484.95 |
| Formula | C22H14ClFN4O2S2 |
| Cas No. | 1135023-19-6 |
| Smiles | N#CC1=C(SC(=C1C2=CC=C(F)C=C2)C)NC(=O)CSC3=NN=C(O3)C=4C=CC(Cl)=CC4 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | DMF: 1 mg/mL (2.06 mM), Sonication is recommended. Ethanol: 1 mg/mL (2.06 mM), Sonication is recommended. DMSO: 1 mg/mL (2.06 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMF/Ethanol/DMSO
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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